Based on the amino acid sequences of each histone, estimate the charge of a histone octamer at ph 7. Assume that histidine residues are uncharged at this ph.

Answers

Answer 1

Assuming histidine residues as uncharged, the total charge of the Histone octamer at pH 7 is +146.

Histone H2A has a total of 26 positively charged residues (Arg + Lys) and 9 negatively charged residues (Asp + Glu).

The net charge is 26 – 9 = + 17

Histone H2B has a total of 28 positively charged residues (Arg + Lys) and 10 negatively charged residues (Asp + Glu).

The net charge is 28 – 10 = + 18

Histone H3 has a total of 31 positively charged residues (Arg + Lys) and 11 negatively charged residues (Asp + Glu).

The net charge is 31 – 11 = + 20

Histone H4 has a total of 25 positively charged residues (Arg + Lys) and 7 negatively charged residues (Asp + Glu).

The net charge is 25 – 7 = + 18

The histone octamer's overall charge is equal to 2 x (17 + 18 + 20 + 18) = +146.

The complete question is:

Based on the amino acid sequences of each histone, estimate the charge of a histone octamer at pH 7. Assume that histidine residues are uncharged at this pH.

Histone H2A

M S G R G K Q G G K A R A K A K T R S S R A G L Q F P V G R V H R L L R K G N Y S E R V G A G A P V Y L A A V L E Y L T A E I L E L A G N A A R D N K K T R I I P R H L Q L A I R N D E E L N K L L G R V T I A Q G G V L P N I Q A V L L P K K T E S H H K A K G K

Histone H2B

M P E P A K S A P A P K K G S K K A V T K A Q K K D G K K R K R S R K E S Y S V Y V Y K V L K Q V H P D T G I S S K A M G I M N S F V N D I F E R I A G E A S R L A H Y N K R S T I T S R E I Q T A V R L L L P G E L A K H A V S E G T K A V T K Y T S S K

Histone H3

M A R T K Q T A R K S T G G K A P R K Q L A T K A A R K S A P S T G G V K K P H R Y R P G T V A L R E I R R Y Q K S T E L L I R K L P F Q R L V R E I A Q D F K T D L R F Q S A A I G A L Q E A S E A Y L V G L F E D T N L C A I H A K R V T I M P K D I Q L A R R I R G E R A

Histone H4

M S G R G K G G K G L G K G G A K R H R K V L R D N I Q G I T K P A I R R L A R R G G V K R I S G L I Y E E T R G V L K V F L E N V I R D A V T Y T E H A K R K T V T A M D V V Y A L K R Q G R T L Y G F G G

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Related Questions

take two carbon atoms and join by two springs making a double bond. complete the ethene moleeule by adding two hydrogen atoms to each carbon atom. each carbon atom should now have the usual four bonds. this is ethene which is also called ethylene. the structure for ethene is

Answers

Ethene (H2C=CH2) is a gaseous by-product of the long-chain hydrocarbons that are cracked to create highly sought-after goods like gasoline and aviation fuels.

What is ethene used for?The uses of ethene include: It is employed in the creation of polythene. It is used to make fruits artificially ripe. Ethene is also utilised to create other beneficial molecules such ethanol, oxyethylene flame, and ethylene glycol, which is used as an antifreeze.Does ethylene resemble ethene?A substance having the chemical formula C2H4 is ethylene, commonly known as ethene. It is both the most easily manufactured organic compound in the world and the simplest alkene. Unsaturated hydrocarbon ethylene, often known as C2H4, is utilised in industrial facilities and is occasionally found in typical medicine cabinets as a hormone.

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a 3.214 g sample of magnesium reacts with 8.416 g of bromine (br2). the only product is magnesium bromide (mgbr2). how much mgbr2 is formed?

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The reaction between 3.214 g magnesium and 8.416 g bromine produces  9.7 g of MgBr2.

The balanced chemical reaction of magnesium and bromine is shown below.

Mg + Br2 → MgBr2

Step 1: Convert the given mass of reactants to moles of reactants

moles Mg = mass Mg / molar mass Mg

moles Mg = 3.214 g / 24.31 g/mol

moles Mg = 0.1322 mol

moles Br2 = mass Br2 / molar mass Br2

moles Br2 = 8.416 g / 159.808 g/mol

moles Br2 = 0.0527 mol

Step 2: Bromine (Br2) is determined to be the limiting reactant. Since the stoichiometric ratio between the reactants is equal to 1, the reactant with a lower number of moles would be the limiting reactant.

Step 3: Convert moles of Br2 to the mass of MgBr2. Their stoichiometric ratio is also 1, which makes the solution easier.

mol Br2 = mol MgBr2

mass MgBr2 = mol MgBr2 * molar mass MgBr2

mass MgBr2 = 0.0527 mol * 184.118 g /mol

mass MgBr2 = 9.70 g

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the general molecular formula for alkanes is cnh2n 2. what is the general molecular formula for cycloalkanes? click in the answer box to activate the palette.

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The cycloalkanes have the general formula CnH2n, where n is the number of carbons.

The carbon atoms of cyclic hydrocarbons, such as cycloalkanes, are organized in the shape of a ring. Additionally saturated, cycloalkanes have single bonds between all of the carbon atoms that make up the ring (no double or triple bonds). Additionally, there are polycyclic alkanes, which are compounds made up of two or more cycloalkanes linked together to form numerous rings.Cycloalkane naming adheres to a straightforward set of guidelines that are based on the same fundamental procedures used to name alkanes. The prefix "cyclo-" is used to identify cyclic hydrocarbons.Numerous organic molecules, referred to as cycloalkanes, can be found in nature or made in a lab and include rings of carbon atoms with distinctive chemical properties.

Therefore, the general formula for cycloalkanes is CnH2n.

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what element makes baking powder so reactive when it touches coke

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Answer: El polvo de hornear obtiene su energía de una reacción química que produce burbujas de aire, mientras que la levadura es un organismo vivo real que produce de gas a partir de una reacción biológica. Los dos procesos no son similares, y tampoco son intercambiables en las recetas.

Baking powder gets its energy from a chemical reaction that produces air bubbles, while yeast is an actual living organism that produces gas from a biological reaction. The two processes are also not similar and are interchangeable in recipes.

Explanation:

Pleaseeeeeee help meeee

Answers

Answer:

2

1

2

3

3

1

Explanation:

In the first law, an object will not change its motion unless a force acts on it.
This is exactly how it worked in the (Last one). There is no movement with no force. The Second one seems a bit strange, but it's been known that inertia is the same as the first law. Why is that? Because there is no force acting on the water but there is some force acting on the glass.

In the second law, the force on an object is equal to its mass times its acceleration.
(First one& Third One) Increasing mass means increasing the force to accelerate with the same magnitude

In the third law, when two objects interact, they apply forces to each other of equal magnitude and opposite direction
The Fifth one. The combustion of the fuel produce force which is greater than the gravititional force acting on the rock. Therefore, a force has a reaction force which accelerates the rock upwards.
The Fourth is pretty much the same. A force of inertia acting as the reaction force here which refuses to move with the paper.
If you didn't get what i mean in any of those please let me know

How do i find the charge?

Answers

Answer:

An easy way to work out the charge of an atom is to look at the periodic table. Elements on the left side of the table usually become positively charged ions and elements on the right side of the table typically have a negative charge. However, you can use a scientific formula to determine the formal charge of an atom.

Explanation:

which metal is best for making metal canister​

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Answer:

Are there any answer choices? There are many options: stainless steel, aluminum, etc.

Explanation:

Reading chemical symbols​

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Answer:

do u need answer for all of them?

Tony walks at an average speed of 70m/min from his house to school. if the distance between his home and the school is 2100 m, how much time does it take for tony to walk to school?

Answers

Tony with an average speed of 70m/min walks the distance from his house to school in a time of: 30 min

The formula and procedure we will use to solve this exercise is:

t = x/v

Where:

x = distance

t = time

v = velocity

Information about the problem:

v = 70m/minx= 2100 mt = ?

Applying the time formula we have that:

t = x/v

t = 2100 m/ (70m/min)

t = 30 min

What is velocity?

It is a physical quantity that indicates the displacement of a mobile per unit of time, it is expressed in units of distance per time, for example (miles/h, km/h).

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a strong acid like hcl . group of answer choices is a strong buffer at low ph dissociates completely in an aqueous solution dissociates completely in aqueous solutions and is a strong buffer at low ph increases the ph when added to an aqueous solution reacts with strong bases to create a buffered solution

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A strong acid like hcl dissociates completely in an aqueous solution

Acid :

A Brnsted-Lowry acid or Lewis acid is a molecule or ion that has the ability to donate a proton or establish a covalent bond with an electron pair. Proton donors, also known as Brnsted-Lowry acids, are the first class of acids.

What is an acid and what does it do?

LSD, sometimes known as acid, is the chemical name for lysergic acid diethylamide. Given that it's a potent psychedelic, you run the risk of seeing things and reality differently if you use it. Tripping is the term used to describe the LSD experience. Acidic substances fall below 7.0, while alkaline or basic substances rise above 7.0.

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Can anyone please explain how to use the formula for the given question with work shown​

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.53 micrometers

take away the zeros and decimal it

How would I find the mass of the statue? Is it conversions or just basic math?

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The replacement of gold from trapped pedestal is a mathematical equation.

What is density?

Density is defined as the measurement of how tightly the material is packed together. It can also be defined as the substance mass per unit volume.

The S.I. unit of density is kilogram per cubic meter.

Density =  mass / volume

Thus, the replacement of gold from trapped pedestal is a mathematical equation.

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Select all of the objects that (essentially) maintain a constant velocity.
A planet in orbit around a star
A hockey puck sliding on the ice
An apple sitting on a table
A baseball after being hit by a bat

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Answer:  baseball after being hit by a bat planet in orbit around a starExplanation:

a material that has more than one set of properties

Answers

Answer:

heterogeneous mixture

Explanation:

the particles of each substance can be seen and the mixture has more than one set of properties.

how is copper obtained and separated from other nearby substances

Answers

Answer:

Explanation:

Copper mining is usually performed using open-pit mining, in which a series of stepped benches are dug deeper and deeper into the earth over time. To remove the ore, boring machinery is used to drill holes into the hard rock, and explosives are inserted into the drill holes to blast and break the rock.

why is baking soda used in soda acid fire extinguisher?​

Answers

Answer:

Explanation:

because seems it has a chemical that can remove fire they added it on a fire extinguisher

Answer:

Explanation:

why is baking soda used as acid fire extinguisher? Carbon dioxide gas is neither combustible nor helps combustion. It is heavier than air and cuts off the supply of oxygen from air and hence extinguishes the fire. … Hence, sodium bicarbonate is used in fire extinguishers.

Explain how gallium and germanium fit in Mendeleev’s predictions

Answers

Mendeleev left gaps in the periodic table to place elements not known at that time. By looking at the chemical properties and physical properties of the elements next to a gap, he predicted the properties of these undiscovered elements.

What is Mendeleev periodic table ? Based on the gaps in the periodic table Mendeleev deduced that in these gaps elements were yet to be discovered. Based on other elements in same group he predicted the existence of eka-aluminum, eka-boron, and eka-silicon, later to be named gallium (Ga), scandium (Sc), and germanium (Ge) respectively.eka-aluminum gallium (Ga)eka-boron scandium (Sc)eka-silicon germanium (Ge)

Thus we can conclude that, the chemical and physical properties of the elements next to the gap, he was able to predict gallium and germanium.

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In 1871, the atomic masses and other chemical characteristics of gallium, germanium, and scandium were unknown, but Mendeleev provided slots for each and made predictions about them.

Mendeleev's PredictionsMendeleev became so certain of the validity of his periodic table that he altered the atomic masses of known elements to make them fit where they "belonged" in it. He did this on the basis of his belief in his table alone, not any experimental evidence. In one instance, he adjusted the beryllium atomic mass from 14, which put it in Group 15 above nitrogen (N), to 9, which moved it below nitrogen. It was positioned in Group 2 above magnesium (Mg), with which it shared a closer chemical relationship. Mendeleev's bold prediction of the properties of as-yet-undiscovered elements was even more audacious.

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why do meteorologists study air pressure

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the answer to this question is D

TASK 3:
Figure 2 shows the chemicals given to a student.
Figure 2
W
Four different powdered metals
X
Y
Z
Dilute
sulfuric
acid
The student wants to investigate the reactivity of the four metals.
Outline a plan the student could use to investigate the relative reactivity of the four
metals, W, X, Y and Z
The plan should use the fact that all four metals react exothermically with dilute
sulfuric acid.
You should name the apparatus used and comment on the safe use of the
chemicals
_(6)

Answers

The apparatus used are dewer vessel 1000ml capacity complete with cover, electric stirrer 300rpm, base with stand, and W = zinc, X = aluminium, Y = magnesium, Z = iron and metals reactivity is chart listing metals in order of decreasing reactivity

Here given data is Four different powdered metals W,X,Y, Z react with Dilute sulfuric acid

When W=zinc, X=aluminium, Y=magnesium, Z=iron this four metals are reactive with Dilute sulfuric acid then give ZnSO₄, Al₂(SO)₃,  MgSO₄, FeSO₄ and magnesium is very active metal and gold and platinum are not react with Dilute sulfuric acid and apparatus used are dewer vessel 1000ml capacity complete with cover, electric stirrer 300rpm, base with stand

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(bonus) Which of the following sets of elements should have the most similar chemical properties? (1 pt)
*
1 point
Sodium (Na, #11), Aluminum (Al, #13), Chlorine (Cl, #17)
Chlorine (Cl, #17), Argon (Ar, #18), Potassium (K, #19)
Beryllium (Be, #4), Calcium (Ca, #20), Radium (Ra, #88)

Answers

Beryllium, Calcium, Radium elements should have the most similar chemical properties.

What are chemical properties?

Chemical properties can be defined as a characteristics or behavior of the substance that be observed when it undergo a chemical change or reaction. Chemical properties may include flammability, toxicity, acidity, basicity, reactivity, heat of combustion and many more.

Beryllium, Calcium and Radium are the elements of alkaline earth metal and the share most of the similar chemical and physical properties.

Thus, Beryllium, Calcium, Radium elements should have the most similar chemical properties.

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1. The physician ordered Azithromycin 15 mg/kg IV star for a child who weighs 20.0 kg. How many mg would the pharmacist need to put in the IV bag?

2. Morphine sulfate is used for pain relief but can also become addicting and fatal. The physician order reads: Morphine sulfate 0.30 mg IM ( intramuscular) stat. The recommended dose is 0.01 mg/kg. Is the ordered dose a mg safe for a child who weighs 31.0 kg?

Answers

1. 15mg/kg x 20.0 kg = 300 mg

2. Yes. 0.01 mg/kg x 31.0 kg = 0.31 mg

1. The pharmacist would need to put 300 mg of Azithromycin in the IV bag for the child.

2. The ordered dose of Morphine sulfate is safe for the child as 0.30 mg is slightly lower than 0.31 mg.

1. Azithromycin dosage for a child who weighs 20.0 kg:

The physician ordered Azithromycin at a dose of 15 mg/kg IV (intravenous) star.

Weight of the child (W) = 20.0 kg

Amount of Azithromycin needed = Weight of the child × Dose per kg

                                                       = 20.0 kg × 15 mg/kg

                                                       = 300 mg

Thus, the pharmacist need to put 300 mg of Azithromycin.

2. Morphine sulfate dosage for a child who weighs 31.0 kg:

The physician ordered Morphine sulfate at a dose of 0.30 mg IM (intramuscular) stat.

Weight of the child (W) = 31.0 kg

Recommended dose of Morphine sulfate = 0.01 mg/kg

                                                                       = 0.01 mg/kg × 31.0 kg

                                                                       = 0.31 mg

The ordered dose of 0.30 mg is slightly lower than the recommended dose of 0.31 mg for a child who weighs 31.0 kg.

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tris (short for tris-(hydroxymethyl)aminomethane) is a commonly used buffer for biochemical solutions. it contains an ionizable amino group with pka

Answers

200ml of 0.1M tris-H with 732ml water and 68ml of 0.1M NaOH

What is the purpose of tris hydroxymethyl aminomethane?

The Food and Drug Administration has approved THAM, a rarely used buffer, for the treatment of metabolic acidosis related to cardiac bypass surgery and metabolic acidosis related to cardiac arrest.

What use does Tris buffer serve?For DNA agarose electrophoresis, Tris buffers are frequently employed. TBE (Tris borate/EDTA) and TAE (Tris acetate/EDTA) are the two major buffers. These Tris buffers can normally be used interchangeably, despite some variations in the resolution of various types of DNA and their mobility during electrophoresis.Using a tris buffer helps keep the pH steady during cell lysis and extraction because DNA extraction is a pH-sensitive procedure.

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the question you are looking for is

Tris-hydroxymethyl aminomethane (TRIS) is widely used for the preparation of buffers in biochemical research. Shown here is the structure of TRIS in its protonated form: Its acid dissociation constant, pKa, is 8.32 x10-9 M. You have available at your lab bench a 0.1 M solution of TRIS in its protonated form, 0.1 Msolutions of HCl and NaOH, and ample distilled water. Describe the preparation of a 1 L solution of 0.02 M TRIS buffer, pH 7.8.

When iron is placed in nitrogen no occurs

Answers

Nothing happens if the iron rod is inserted into the nitrogen. However, when the iron rod is suspended in the air.

A non-metal, nitrogen is. As a result, it typically interacts with metals to create ionic compounds. Only when the reactants produce products that allow the system as a whole to release energy does the reaction take place. If the system requires energy to undergo the reaction, the reaction cannot take place. When iron is exposed to oxygen and moisture for an extended length of time, a process known as iron oxide occurs. At the atomic level, oxygen bonds to iron to produce the complex known as an oxide, which weakens the metal bond.

The complete question is - If a piece of pure iron is placed in pure nitrogen, nothing happens. If the iron is exposed to air, it begins to rust. What conclusion can you make about air, based on this observation?

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In this experiment you are going to use 100. Mg of sodium borohydride. How many moles of sodium borohydride will you use?.

Answers

0.00264 moles of sodium borohydride will be used.

m(NaBH₄) = 100 mg ÷ 1000 mg/g

m(NaBH₄) = 0.1 g; mass of sodium borohydride

M(NaBH₄) = 37.83 g/mol; molar mass of sodium borohydride

n(NaBH₄) = m(NaBH₄) ÷ M(NaBH₄)

n(NaBH₄) = 0.1 g ÷ 37.83 g/mol

n(NaBH₄) = 0.00264 mol; amount of sodium borohydride

Sodium borohydride is white solid and it is a reducing agent.

Sodium tetrahydridoborate is an inorganic compound with the formula NaBH₄.

Mass is a fundamental measure of the amount of matter in the object.

Kilogram (symbol: kg) is the base unit of mass in the International System of Units.

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Periodic Table Project: Element Presentation Your Favorite Element Student Guide Assignment Prompt In this assignment, you will research an element of your choice from the periodic table. Using reference materials and Internet sites, you will collect information about the element.

Answers

The element from the periodic table which is choose is Hydrogen.

Behaviour of hydrogen atom as electronegative atom

Hydrogen behaves as electronegative atom when it combine with the elements of group 1 and group 2. Since, hydrogen have the capability to accept an electron to acquire stable noble gas electronic configuration like helium.

Behaviour of hydrogen atom as electropositive atom

Hydrogen behaves as electropositive atom when it combine with the elements of group 13, 14, 15, 16 and group 17. Since, hydrogen have the capability to lose an electron to acquire stable noble gas electronic configuration.

Thus, from. above we concluded that hydrogen have unique property rather than another elements. So, it is best suited for assignment project.

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Using the periodic table above and your knowledge of patterns and trends on the table, which of the following elements is the best conductor of electricity? (1 pt)
*
1 point
Titanium (Ti, #22)
Silicon (Si, #14)
Oxygen (O, #8)
Argon (Ar, #18)

Answers

The metals are good conductor of electricity, thus among this titanium is the best conductor of electricity.

What are conductors?

Conductors is defined as a substance or type of material that allow flow of charge or electricity in one or more direction. Metals are commonly consider as a good conductor of electricity. It allow electricity to flow through them very easily and produce electric current.

Metals are defined as the elements that are typically hard due to presence of strong metallic connection between the atoms.

Thus, metals are good conductor of electricity, thus among this titanium is the best conductor of electricity.

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during a gravimetric analysis experiment to determine the salt (nacl) content of a chicken soup sample, a precipitate of silver chloride was produced, dried and weighed. the sources of error in the analysis include

Answers

Some precipitate remained in the reaction flask after the filtration process, which is one of the sources of mistake in the analysis.

Where is the use of gravimetric analysis?

Gravimetric analysis has several practical applications, such as monitoring lead concentrations in drinking water, which, if left unchecked, could result in lead poisoning and even death.

How does a gravimetric analysis work?

After the sample has been dissolved, the stages necessary for gravimetric analysis are as follows: solution preparation, precipitation, digestion, filtration, washing, drying or igniting, weighing, and finally calculation.

The principle of gravitational analysis:The idea underlying gravimetric analysis is that it is possible to determine the mass of an ion in a pure substance. The mass percent of the same ion in a known quantity of an impure chemical is later determined using this method.

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the question you are looking for is

During a gravimetric analysis experiment to determine the salt (NaCl) content of a chicken soup sample, a precipitate of silver chloride was produced, dried and weighed. The sources of error in the analysis include

I)The precipitate was not washed before it was dried.

II)The soup contained some sodium iodide in addition to the sodium chloride.

III)Some precipitate remained in the reaction flask after the filtration process.

Which of these errors could account for a lower than expected mass of silver chloride precipitate?

what do you think will happen to the temperature if you use 75 ml of hcl and 75 ml of naoh instead of the 50 ml each that you used in experiment 1?

Answers

The thing that will happen to the temperature if you use 75 ml of HCl and 75 ml of NaOH instead is that it increases as more heat is released.

How to explain the reaction?

A neutralization occurs when NaOH and HCl are combined. Each chemical reaction has a unique heat of reaction, which is the heat exchanged during the process.

The reaction in issue is exothermic (emits heat), and the amount of heat emitted relies on the chemicals used, their concentrations, and the working temperature (it is produced at a low temperature).

The fluctuation in temperature and the mass used determine how much heat is allocated.

In this case, the thing that will happen to the temperature if you use 75 ml of HCl and 75 ml of NaOH instead is that it increases as more heat is released.

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A rock will scratch with a fingernail but not a copper penny. According to mohs hardness scale, what can the student determine about the rock?

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A rock will scratch with a fingernail but not a copper penny then according to Mohs hardness scale, the student will determine that the rock is more harder than fingernail and copper penny.

What is Mohs hardness scale?

Mohs hardness scale can be defined as a qualitative ordinal scale ranges from one to ten characterizing the scratch resistance of various minerals through the ability of harder material to the softer material.

Hardness can be defined as the measure of the material resistance to localized permanent deformation. Permanent deformation is also known as plastic deformation.

Thus,  rock will scratch with a fingernail but not a copper penny then according to Mohs hardness scale, the student will determine that the rock is more harder than fingernail and copper penny.

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please answer these questions. im sure im wrong on all them!!!!! please answer correctly too

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Answer:

the graph shows that the filtrated solution was acidic but when we add nh3 (base) ,acid base reaction take place and in this reaction salt and water are form by this oh-ion concentration keep on increasing and change ph from 4 to 10

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