Figgie he, 3rd, inglis ae, goldberg vm, ranawat cs, figgie mp, wile jm. an analysis of factors affecting the long-term results of total shoulder arthroplasty in inflammatory arthritis.
J arthroplasty. 1988;3:123–130.The given citation is the source of information on the subject "factors affecting the long-term results of total shoulder arthroplasty in inflammatory arthritis".
It is from the journal named 'J Arthroplasty' that was published in the year 1988. The paper was written by a team of authors, namely Figgie HE, 3rd, Inglis AE, Goldberg VM, Ranawat CS, Figgie MP, and Wile JM.
Total shoulder arthroplasty (TSA) is a surgical procedure used to replace a damaged or injured shoulder joint with an artificial joint. This procedure is frequently used to treat patients with inflammatory arthritis.
The long-term outcomes of total shoulder arthroplasty in patients with inflammatory arthritis can be influenced by various factors. Some of the factors are as follows:
1. Age
2. Gender
3. General health
4. Smoking
5. Body mass index (BMI)
6. The severity of the condition
7. Quality of the implant
8. Quality of the surgical technique.
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The complete question is,
Figgie He, Third, Inglis A, Goldberg V, Ranawat C, Figgie mp, and Wile J. an examination of variables influencing total shoulder replacement outcomes in inflammatory arthritis. 1988;3:123–130 in J Arthroplasty.
QUESTION 1 The smallest independently functioning biological unit of an organism is a(n). cell molecule organ tissue QUESTION 2 A collection of similar tissues that performs a specific function is an organ organelle organism organ system QUESTION 3 The body system responsible for structural support and movement is the cardiovascular system endocrine system muscular system skeletal system
The smallest independently functioning biological unit of an organism is a cell. A cell is the smallest independently functioning biological unit of an organism.
Cells come in different shapes and sizes and can be found in every living organism. They perform all the functions necessary for life. A collection of similar tissues that performs a specific function is an organ. Organs are collections of similar tissues that work together to perform a specific function in the body. Organs are formed by the combination of two or more tissues. Each organ performs a specific function in the body.
Examples of organs include the heart, lungs, liver, and kidneys. The body system responsible for structural support and movement is the skeletal system. The skeletal system is responsible for structural support and movement in the body. It consists of bones, cartilage, ligaments, and other connective tissues that provide support and structure to the body. The skeletal system also protects the internal organs and produces blood cells.
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The smallest independently functioning biological unit of an organism is a cell. These cells combine to create tissues, which in turn form organs that carry out specific functions. Organ systems, such as the skeletal system, are groups of functionally related organs.
Explanation:The smallest independently functioning unit of an organism is commonly referred to as a cell. This includes all living structures, from human anatomy to bacteria, which is a single-celled organism.
The next level of biological organization incorporates cells into tissues, which are groups of similar cells working together to perform related functions. These tissues then combine to form an organ, which is a collection of tissues grouped together to perform a specific function.
The skeletal system is responsible for providing structural support and facilitating movement in the body. It is an example of an organ system, a higher level of organization that includes functionally related organs.
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9. Explain what is meant by the statement "Metabotropic receptors act via second messengers."
10. Explain why it is the receptor and not the neurotransmitter that determines whether the postsynaptic membrane produces an EPSP or an IPSP.
11. A kangaroo is able to increase greatly its rate of movement on a flat surface without appreciable cost of transport. Yet, when it is forced to jump uphill, its oxygen consumption spikes tremendously. Why is this?
12. How do motor units regulate the force of muscle contraction?
13. Why doesn't a muscle continue to contract once the calcium is released?
14. Why don't postsynaptic membranes continue to depolarize after a neurotransmitter binds to their receptors?
The statement "Metabotropic receptors act via second messengers" means that the receptor itself does not act as an ion channel.
Instead, it is coupled to a G protein, which in turn activates an enzyme that produces a second messenger. The second messenger then acts on ion channels or other intracellular targets to produce an effect. The receptor, not the neurotransmitter, determines whether the postsynaptic membrane produces an EPSP or an IPSP. This is because the same neurotransmitter can bind to different types of receptors, each of which may produce a different effect. For example, acetylcholine can bind to nicotinic receptors, which produce EPSPs, or muscarinic receptors, which produce IPSPs.
When a kangaroo is forced to jump uphill, its oxygen consumption spikes tremendously because uphill jumping requires much more work than flat surface movement. The kangaroo must overcome the force of gravity, which requires energy. Additionally, the kangaroo must accelerate its body upwards, which requires additional energy. Motor units regulate the force of muscle contraction by varying the number and size of muscle fibers they innervate. A motor unit consists of a motor neuron and all the muscle fibers it innervates. When a motor neuron fires, all the muscle fibers in its motor unit contract. The force of contraction depends on the number of muscle fibers contracting and the frequency of motor neuron firing.
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How do muscular strength and muscular endurance differ? Describe
a scenario where you would have to determine whether to measure
strength or endurance and which test(s) you would need to use.
Muscular strength is maximum force, while endurance is sustained contractions. Choose based on activity: 1RM for strength, push-ups or cycling for endurance.
Muscular strength and muscular endurance are two different components of muscular fitness.
Muscular strength refers to the maximum force or tension a muscle or group of muscles can generate in a single contraction. It is typically measured by determining the maximum amount of weight an individual can lift, push, or pull in a specific exercise, such as a one-repetition maximum (1RM) test. Muscular strength is important for activities that require short bursts of intense effort, such as weightlifting, powerlifting, or performing a single maximum effort lift in sports like shot put or javelin throw.
Muscular endurance, on the other hand, is the ability of a muscle or group of muscles to sustain repeated contractions over an extended period. It focuses on the capacity to perform multiple repetitions or sustain a contraction for an extended time without experiencing fatigue. Muscular endurance can be measured through tests like push-up or sit-up tests, plank holds, or timed exercises. It is crucial for activities that involve prolonged effort, such as distance running, cycling, swimming, or participating in team sports like soccer or basketball.
To determine whether to measure muscular strength or endurance, you need to consider the specific requirements of the activity or goal you're assessing. Here's a scenario to illustrate this:
Scenario: You are a fitness trainer working with a group of clients who are preparing for a long-distance cycling event. They need to improve their lower body muscular fitness to pedal efficiently over an extended period.
In this scenario, you would need to assess their muscular endurance because the cycling event requires sustained effort rather than maximum strength for a single movement. To measure their muscular endurance, you could use tests such as:
Squat Jumps: This test measures lower body endurance. Clients perform as many squat jumps as possible within a given time frame, such as one minute, to assess their ability to repeatedly exert force.Wall Sits: This test targets the lower body and assesses isometric endurance. Clients sit against a wall with their knees bent at a 90-degree angle and maintain the position for as long as possible to evaluate their muscle endurance and stability.Cycling Time Trials: Conducting time trials on stationary bikes or outdoor cycling tracks can assess both cardiovascular endurance and lower body muscular endurance. The clients' ability to maintain a steady pace or achieve specific distances within given time frames can indicate their endurance levels.By using these tests, you can evaluate the clients' muscular endurance and tailor their training programs to improve their ability to sustain the required effort during the long-distance cycling event.
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answer the questions:
1.what is glucosuria or glycosuria?
2. what is paracellular transport ?
3.GFR is controlled primarily by regulating blood flow through the renal arterioles. what is relation of GFR with increased resistance in afferent arteriole
Glucosuria or glycosuria is the medical term used to describe the presence of glucose in urine.
1. This may occur when the concentration of glucose in the blood exceeds the renal threshold for glucose reabsorption, which results in glucose being excreted in the urine. It is often a sign of diabetes or other conditions that affect glucose regulation in the body.
2. Paracellular transport refers to the movement of substances between cells that occurs through the tight junctions between adjacent cells. This transport mechanism is passive and is driven by concentration gradients and the movement of water across the cell membranes. It plays an important role in the absorption and secretion of substances across epithelial barriers.
3. GFR (glomerular filtration rate) is the measure of the amount of fluid that is filtered through the glomeruli of the kidneys per unit time. It is primarily controlled by regulating blood flow through the renal arterioles. When there is increased resistance in the afferent arteriole, this reduces the blood flow into the glomerulus, which in turn decreases GFR. Conversely, decreased resistance in the afferent arteriole increases blood flow into the glomerulus and increases GFR.
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27. Select all ions below that are reabsorbed by the renal system. (Hint* they are moved from the nephron into the blood system)
- NA (sodium)
- K (Potassium)
- CI (chloride)
- H (hydrogen/hydronium)
- HCO3 (bicarbonate)
- Glucose
33. choose your favorite mode of inheritance and give a specific example that demonstrates it (preferably real, but you can make up a gene), include the results you'd see from the progeny (kids)
27. The following ions are reabsorbed by the renal system are: NA (sodium)K (Potassium)CI (chloride)HCO3 (bicarbonate)The ions that are reabsorbed by the renal system include sodium, potassium, chloride and bicarbonate. They are reabsorbed from the nephron and into the bloodstream. Hydrogen ions are secreted into the tubular fluid while glucose is reabsorbed by the proximal tubule and can be observed in the blood.
33. Mode of inheritance: Autosomal dominant inheritance is the most common mode of inheritance. An example that demonstrates it: Huntington’s disease is an inherited condition that is caused by a single gene which is autosomal dominant. It is a neurological disorder characterized by degeneration of nerve cells in the brain and results in involuntary movement, cognitive decline, and dementia.
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Table of Functions Structure Function/Purpose/Interesting Detail Mucosa- epithelium __________
Mucosa - lamina propria __________
Muscularis mucosae ___________
Muscularis externa _______________
Serosa/adventitia (visceral peritoneum) _________
A brief explanation of each structure and its function/purpose is given below.
Mucosa - epithelium:
Forms the innermost layer of the mucosa. It serves as a protective barrier. Can have specialized functions such as absorption or secretion depending on the specific location in the body.Mucosa - lamina propria
The layer of loose connective tissue beneath the mucosal epithelium. It contains blood vessels, lymphatic vessels, and immune cells. It provides support and nourishment to the overlying epithelium.Muscularis mucosae
A thin layer of smooth muscle is located beneath the lamina propria. It helps with the movement and folding of the mucosa, increasing its surface area.Muscularis externa
A thick layer of smooth muscle is responsible for the motility and movement of the organ. It contracts and relaxes to propel and mix contents within the organ.Serosa/adventitia (visceral peritoneum)
The outermost layer of the organ wall. It is composed of connective tissue and can be either a serosa (when the organ is covered by the visceral peritoneum) or an adventitia (when the organ is not covered by the peritoneum). It provides support and protection to the underlying structures.Therefore, the following points are the function/ purpose of each of them.
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Briefly describe in one paragraph, how the
bodyprotects us
from infection,
and list
the main body systems involved in this process.
The body protects us from infection through the immune system. The immune system is composed of more than 100 billion immune cells that work together to identify and destroy foreign invaders such as bacteria, viruses, and parasites.
The main body systems involved in this process are the lymphatic system, which produces and transports white blood cells, and the circulatory system, which transports these cells to various parts of the body to fight off infection. The skin and mucous membranes also play a role in protecting the body by creating physical barriers that prevent pathogens from entering the body. Additionally, the respiratory system helps to filter out harmful particles in the air we breathe, while the digestive system destroys harmful bacteria in the food we eat.
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Fetal alcohol syndrome is the leading cause of in the Western world. OA. PIntellectual impairment OB. Infertility OC. Multiple births OD. Miscarriages QUESTION 10 One reason that dieting may not work is OA. a high BMR. OB. an insensitive BMR. OC. a low BMR. OD. None of the above.
Fetal alcohol syndrome is the leading cause of intellectual impairment in the Western world. Hence option A is correct.
Fetal alcohol syndrome is the leading cause of intellectual impairment in the Western world. This is the accurate statement related to the given question. It is a condition in which a baby is born with mental and physical defects due to the mother's alcohol consumption during pregnancy.
Let's look at the reason why dieting may not work: Dieting may not work due to a low BMR. The Basal Metabolic Rate (BMR) is the number of calories the body requires at rest to perform its basic functions such as breathing, circulation, and cell production. As a result, an individual with a low BMR has a slower metabolic rate, making it more difficult to burn calories and lose weight. Therefore, option C is the correct answer: a low BMR.
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The cell that migrates from the outside to the inside of the blood-testis barrier is Select one: a. a primary spermatocyte. b. a type B spermatogonium. c. a secondary spermatocyte. d. a spermatid. e. a type A spermatogonium.
The correct answer is A. A spermatogonium. In the process of spermatogenesis, which is the production of sperm cells, type A spermatogonia are the stem cells that reside on the periphery of the seminiferous tubules in the testes.
These cells undergo mitotic divisions to replenish the population of spermatogonia and also give rise to other types of spermatogonia. When a type A spermatogonium undergoes further division and differentiation, it transforms into a type B spermatogonium. These type B spermatogonia are the cells that migrate from the outside to the inside of the blood-testis barrier.
This barrier is a specialized structure that separates the seminiferous tubules from the bloodstream to create an immune-privileged environment for spermatogenesis. Once inside the blood-testis barrier, type B spermatogonia further differentiate into primary spermatocytes, which then undergo meiosis to form secondary spermatocytes and eventually spermatids. These spermatids undergo further maturation to become functional sperm cells.
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41. all of the following is information traveling to the cerebrum in the fasiculus gracilis and fasiculus cuneatus except a. proprioception b. pain c. vibration d. weight discrimination e. stereognosis 42. All of the following are under ANS control except -a. withdrawal reflex b. coughing c. sneezing d. swallowing
All the information traveling to the cerebrum in the fasciculus gracilis and fasciculus cuneatus includes touch, vibration, proprioception, weight discrimination, and stereognosis, except for pain. The correct option is b. pain.
Explanation:
The fasciculus gracilis and fasciculus cuneatus are ascending tracts in the spinal cord that transmit sensory information from the limbs to the brainstem.
They carry touch, vibration, proprioception, weight discrimination, and stereognosis information from different parts of the body to the cerebrum for processing.
Regarding the autonomic nervous system (ANS), it controls involuntary bodily functions.
Coughing (option b), sneezing, and swallowing are reflex actions rather than functions directly regulated by the ANS.
Therefore, the correct answer is option b. coughing.
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Myriad Genetics 1) patented "life" materials, or genetic materials (the BRCA1 and BRCA2 genes) 2) assisted in Dr. Ananda Chakrabarty's work on the pseudomonas "superbug" 3) legally controlled the right to test for certain genes 4) a. and b. 5) b. and c. 6) a. and c. 7) a., b., and c.
Myriad Genetics is involved in patenting genetic materials, assisting in scientific research, and controlling the right to test for certain genes. Option 7 is the correct answer.
Myriad Genetics has been involved in all of the mentioned activities. They have patented genetic materials, specifically the BRCA1 and BRCA2 genes, which are associated with an increased risk of breast and ovarian cancer.
They also assisted Dr. Ananda Chakrabarty in his work on the pseudomonas "superbug," which involved genetic modification. Additionally, Myriad Genetics has obtained legal control over the right to test for certain genes, including the BRCA1 and BRCA2 genes, which has sparked debates regarding gene patenting and access to genetic testing.
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Broadly, what category of cellular receptors do beta blockers act on?
A. GATA-2 receptors
B. Adrenergic receptors
C. Acetylcholine receptors
D. Androgen receptors
Beta-blockers primarily act on adrenergic receptors. Here option B is the correct answer.
Adrenergic receptors are a class of cellular receptors that respond to the neurotransmitter and hormone called norepinephrine (noradrenaline) and its close chemical cousin, epinephrine (adrenaline). These receptors are part of the sympathetic nervous system, which is responsible for the body's "fight or flight" response.
There are two major types of adrenergic receptors: alpha receptors and beta receptors. Beta-blockers specifically target the beta receptors. There are three subtypes of beta receptors: beta-1 (β1), beta-2 (β2), and beta-3 (β3). Beta-blockers can selectively block beta-1 receptors, non-selectively block both beta-1 and beta-2 receptors, or have additional effects on other receptors.
By blocking beta receptors, beta-blockers interfere with the binding of norepinephrine and epinephrine to these receptors. This leads to a reduction in the effects of sympathetic nervous system stimulation, such as decreased heart rate, decreased force of contraction of the heart, and reduced blood pressure.
Beta-blockers are commonly used to treat conditions such as hypertension (high blood pressure), angina (chest pain), arrhythmias (abnormal heart rhythms), and heart failure. Therefore option B is the correct answer.
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Explain the humoral control of the circulation.
The humoral control of circulation refers to the regulation of blood flow and blood pressure by various chemical substances, known as humoral factors, that are present in the blood. These factors include hormones, enzymes, and other molecules that act as messengers to communicate with different organs and tissues involved in controlling the circulation.
One of the key humoral factors involved in circulatory control is the hormone called angiotensin II. It is produced by the activation of the renin-angiotensin system in response to low blood pressure or decreased blood flow to the kidneys. Angiotensin II acts on blood vessels to cause vasoconstriction, narrowing the vessels and increasing blood pressure. It also stimulates the release of aldosterone, a hormone that promotes salt and water retention by the kidneys, further increasing blood volume and pressure.
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During male puberty, the prostate gland normally increases in size. Which of the following hormones is the most likely cause of the prostate enlargement at this stage of development A) Androstenedione B) Dehydroepiandrosterone C) Dihydrotestosterone
D) Follicle-stimulating hormone E) Growth hormone F) Insulin-like growth factor-il G) Testosterone
During male puberty, the prostate gland normally increases in size. The most likely cause of prostate enlargement at this stage of development is D) Dihydrotestosterone (DHT).
Dihydrotestosterone is a hormone derived from testosterone, which is responsible for the growth and development of male sex characteristics. DHT is a biologically active hormone and is involved in several male biological processes such as puberty, fertility, hair growth, and prostate enlargement. It plays a vital role in the growth and development of male genitalia, including the prostate gland.
During male puberty, the body produces more testosterone, and as a result, more DHT is produced by the 5-alpha-reductase enzyme. The increase in DHT levels during puberty causes the prostate gland to grow in size. It is a necessary physiological process, but in some men, it can lead to the development of benign prostatic hyperplasia (BPH) later in life. Hence, D is the correct option.
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During a functional reach activity, what muscles are active concentrically, eccentrically, and as stabilizers? What is the plane and axis for each joint (ankles, knees, hips, torso, shoulders, elbows, hand/wrist) in this exercise?
During a functional reach activity, the following muscles are active concentrically, eccentrically, and as stabilizers;Rectus abdominis, External obliques, Internal obliques, Erector spinae (eccentric), Hip abductors, Hip extensors, Hip flexors (concentric), Hamstrings (eccentric), Gastrocnemius, Soleus, Deltoids (anterior), Supraspinatus, Biceps (concentric), Triceps (eccentric).
The plane and axis for each joint (ankles, knees, hips, torso, shoulders, elbows, hand/wrist) in this exercise are;Ankles: sagittal plane, transverse axis.Knees: sagittal plane, transverse axis.Hips: sagittal plane, frontal axis.Torso: sagittal plane, frontal axis.Shoulders: transverse plane, longitudinal axis.Elbow: sagittal plane, transverse axis.Hand/wrist: sagittal plane, longitudinal axis.
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Kidneys are involved in maintaining the homeostasis of all fo the following except a. water balance of blood b. calcium balance of blood c. electrolyte balance of blood d. pH balance of blood
Kidneys are involved in maintaining the homeostasis of all of the following except option B: calcium balance of blood.
Kidneys play a crucial role in maintaining homeostasis, which refers to the body's ability to maintain a stable internal environment. They perform several functions that contribute to maintaining the balance of various substances in the blood, such as water, electrolytes, and pH.
The kidneys are not directly involved in regulating the calcium balance of the blood. Calcium homeostasis is primarily regulated by other organs, such as the parathyroid glands, which secrete parathyroid hormone (PTH) to control calcium levels. PTH acts on the bones, intestines, and kidneys to maintain calcium balance.
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Which of the following statements are correct regarding the surgical knot?
i. The threads we loped around each other twice in the first throw ii. it to ked ty placing square knots on lop iii. One end of the thread is held in one hand at all times leaving the other end and hand free a. At of the mentioned statements b. Only i and iii
c. Only i and ii d. Only ii and iii
e. Only ii
The correct option for the following statement regarding the surgical knot is the option (c) Only i and ii. Below are the explanations of each statement.
i. The threads we loped around each other twice in the first throwThe first throw of the surgical knot involves loping the thread around each other twice.
ii. It tooked by placing square knots on lopIn this statement, it means that the knot is tied by placing a square knot on the loop.
iii. One end of the thread is held in one hand at all times leaving the other end and hand freeIn this statement, it is talking about the position of the thread when tying the surgical knot. One end of the thread is held in one hand at all times leaving the other end and hand free.Thus, the correct option is (c) Only i and ii.
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Biology refers to a person's genetic predispositions. True False
Biology refers to a person's genetic predispositions. This statement is True. Biology is the study of living organisms and how they interact with one another, and this includes the study of genetics.
Which is the study of heredity. Heredity is the passing of genetic traits from one generation to the next, and these traits are passed down through DNA. This means that a person's genetic predispositions, or their likelihood of inheriting certain traits, are determined by their biology.
There are several genetic factors that can influence a person's predisposition to certain diseases or conditions, such as family history, inherited genetic mutations, and gene expression patterns. For example, certain genetic mutations can increase a person's risk of developing cancer, while other mutations can protect against it.
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over a span of 50 years, civil engineers built wildlife bridges to allow animals to safety cross highways that run through a forest. The first graph shows the change in the number of wildlife bridges during those 50 years . The second graph shows a deer population in the same area changed over the same period. Which hypothesis is supported by the data?
The hypothesis supported by the data is that the construction of wildlife bridges has positively impacted the deer population in the area.
The first graph shows an increasing trend in the number of wildlife bridges over the span of 50 years. This indicates that civil engineers have been actively constructing more bridges to facilitate safe animal crossings.
The second graph, depicting the deer population, shows an upward trend over the same period. This suggests that the deer population has increased over time.
Based on these two pieces of information, it can be inferred that the construction of wildlife bridges has provided a safe passage for deer and other wildlife, allowing them to move across the highways more freely and reducing the risk of road accidents and mortality.
This has likely contributed to the growth of the deer population in the area. The data supports the hypothesis that the implementation of wildlife bridges has had a positive impact on the deer population.
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SCENARIO #3: An astronaut has just returned to earth after an extended period in space. Due to the microgravity of space they have experienced significant atrophy of both their skeletal muscles and their bones. They are currently undergoing extensive physical therapy to regain their lost muscle/bone mass. For each of the following statements, say whether you think the statement is TRUE or FALSE, followed by a short justification of why you came to that conclusion. The bone loss that the astronaut experienced in space was likely due to the activity of their osteoclasts outpacing the activity of their osteoblasts. cal When performing rehab exercises with heavy weights, the astronaut is relying more on fast-twitch muscle fibres which are resistant to fatigue and have more mitochondria than slow twitch muscle fibres.
The bone loss that the astronaut experienced in space was likely due to the activity of their osteoclasts outpacing the activity of their osteoblasts - TRUE.
The statement is true because during space flight, the lack of gravity causes a decrease in mechanical loading on bones, leading to decreased bone mass and strength. The lack of weight-bearing activities decreases mechanical loading on bones, and in response to this, the body increases the activity of osteoclasts, leading to increased bone resorption. Therefore, osteoclast activity outpaces osteoblast activity, resulting in bone loss.
The rehab exercises with heavy weights, the astronaut is relying more on fast-twitch muscle fibers which are resistant to fatigue and have more mitochondria than slow twitch muscle fibers - FALSE. The statement is false because heavy weights primarily activate slow-twitch muscle fibers. The slow-twitch fibers are essential for long-term endurance activities, like walking, jogging, and swimming. They are resistant to fatigue and have more mitochondria than fast-twitch fibers. In contrast, fast-twitch fibers are activated for brief, high-intensity activities like sprinting or jumping. They are susceptible to fatigue and have fewer mitochondria than slow-twitch fibers.
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The olfactory epithelium does NOT include:
Olfactory receptor cell
Olfactory vesicle
Glomerulus
Supporting cell
Basal cell
The olfactory epithelium does NOT include glomerulus.
What is the olfactory epithelium?The olfactory epithelium is a specialized tissue located in the upper nasal cavity. It's composed of different cell types that work together to sense and transmit odors to the brain. The olfactory receptor cells, which are sensory neurons that contain specialized proteins called receptors that detect odor molecules, are among the cell types. The olfactory receptor cells are responsible for detecting odors and transmitting signals to the brain through the olfactory nerve.
The olfactory epithelium also contains supporting cells, which provide structural and metabolic support to the olfactory receptor cells; basal cells, which are immature cells that differentiate into olfactory receptor cells and replace old or damaged ones; and Bowman's glands, which are mucus-secreting glands that aid in odor detection by dissolving odor molecules.
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While fluid, electrolytes, and acid-base balance essential to maintaining homeostasis, an imbalance can unknowingly occur with hyperventilation, this discussion, compare the risks and benefits of sports drinks and energy drinks versus plain water. Under what circumstances would each of the bese harmful.
Sports drinks and energy drinks have their benefits and drawbacks. While they can provide a quick source of energy and essential minerals, they are also high in calories and sugar, which can lead to weight gain and other health problems.
Fluid, electrolytes, and acid-base balance are essential to maintaining homeostasis. Any imbalance can unknowingly occur with hyperventilation. Sports drinks and energy drinks have gained popularity in recent years. They are used to rehydrate after a workout and to provide the necessary energy to get through the day. These drinks are not only a source of calories but also essential minerals.
However, it is important to know the risks and benefits of these drinks versus plain water.Risks and benefits of sports drinksSports drinks are beneficial to people who are engaging in strenuous activity. These drinks are recommended for athletes who need to replenish fluids lost due to sweating and exertion. Sports drinks contain electrolytes, which are essential minerals that the body needs to function properly. The glucose in these drinks is also useful in providing a quick source of energy.
However, these drinks are also high in calories and sugar, which can lead to weight gain and health problems like diabetes.Risks and benefits of energy drinks Energy drinks, on the other hand, are designed to provide a quick source of energy. They contain high levels of caffeine and other stimulants that increase alertness and concentration. Energy drinks are also high in calories and sugar, which can lead to weight gain and other health problems. However, they are not recommended for people with heart conditions, high blood pressure, or diabetes, as they can cause an increase in blood pressure and heart rate.
Circumstances in which they can be harmfulSports drinks are not recommended for people who are trying to lose weight, as they contain a significant amount of calories and sugar. They are also not recommended for people who are not engaging in strenuous activity, as they can lead to weight gain and other health problems.
Energy drinks should be avoided by people with heart conditions, high blood pressure, or diabetes. They are also not recommended for children or teenagers, as they can lead to an increase in blood pressure and heart rate, which can be dangerous.
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Identify the largest blood vessel. O Interlobar artery O Peritubular capillaries O Segmental artery O Interlobular artery O Efferent arteriole
The largest blood vessel is the E) Efferent arteriole.
The renal circulation is an essential part of the human circulatory system. The renal arteries supply the kidneys with oxygenated blood and drain the deoxygenated blood to the renal vein, which is a branch of the inferior vena cava. Within the kidney, blood flows through a complex network of blood vessels before it is excreted in the form of urine. The blood vessels within the kidneys are responsible for transporting blood to and from the kidneys' nephrons, where filtration and excretion occur.
As a result, it is important to understand the various blood vessels' roles and functions in the kidneys.
The afferent arterioles supply the glomerulus with oxygenated blood and transport it to the renal corpuscle.
The Efferent arterioles are blood vessels that drain blood from the glomerulus and transport it to the peritubular capillaries or the vasa recta in a process known as ultrafiltration.
Hence, the Efferent arteriole is the largest blood vessel. Option (E) is the correct option.
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Question 3. On a freezing February morning in Boston, a 45-year-old professor decides to warm his car in the garage and waits nearby. About 30 minutes later, his wife finds him confused and breathing rapidly. She takes him to the emergency department at the Boston Medical Center where he is given 100% O2 to breathe. Explanation of Case. The man inhaled the exhaust fumes from his automobile and is suffering from acute carbon monoxide (CO) poisoning. Co binds avidly to hemoglobin (Hb), with an affinity that is 250 times that of Oz-binding to hemoglobin. Thus, some of heme groups that are normally bound to O2 are instead bound to CO, which lowers oxygen saturation as shown below (50% COHb curve). The following constants may be useful throughout this problem: In the absence of CO: O2 saturation Hill constant = 2.5, Pso = 25 mmHg. Henry's Law constant for O2 in blood = 0.003 mL O2 dL1 mmHg 1. Hemoglobin Oz capacity = 1.34 mL O2 (gram Hb) 4. a. The man maintains a systolic blood pressure of 140 mmHg and a diastolic blood pressure of 95 mmHg, a heart rate of 65 bpm, and a stroke volume of 80 ml. Determine his cardiac output (in ml min-1) and total peripheral resistance, assuming a negligible right atrial pressure. b. The man's hemoglobin concentration is 14 g L-1. Prior to CO exposure, his arterial blood Poz is 100 mmHg and his mixed venous blood Poz is 40 mmHg. Determine the O2 content in arterial blood and mixed venous blood (in mL O2 dL-) before CO poisoning. C. What is the man's Oz consumption rate prior to CO exposure (in mL O2 min -)? d. Assume that the man's arterial Poz is not affected by CO and remains at 100 mmHg. Determine the man's O2 content in arterial blood (in mL O2 dL) following exposure to CO. e. Assuming that his Oz consumption rate does not change, use the figure to estimate graphically the man's mixed venous blood Poz following exposure to CO. Explain your reasoning. f. Breathing 100% O2 can lead to atelectasis (the collapse of part of the lung). Explain why in 2-3 sentences. 1 20 0.9 18 0.8 16 0.7 14 0.6 12 Percent Hbo, saturation (%) 0.5 10 O2 content (mL 02/100 ml blood) 50% COHb 0.4 0.3 0.2 0.1 2 0 0 0 100 10 90 20 30 40 50 60 70 80 Oxygen partial pressure (mmHg)
a) Calculation of Cardiac output:
Cardiac output (CO) is calculated by multiplying the stroke volume (SV) with the heart rate (HR).
Stroke volume (SV) = 80 ml
Heart rate (HR) = 65 bpm
CO = SV x HR = 80 ml x 65 bpm = 5200 ml/min
Total peripheral resistance (TPR) is the resistance of the arteries to blood flow and is represented in units of mmHg per minute per mL.
TPR = (MAP - CVP) / CO
Where:
MAP is the mean arterial pressure
CVP is the central venous pressure
MAP = (2/3 DBP) + (1/3 SBP)
MAP = (2/3 x 95 mmHg) + (1/3 x 140 mmHg) = 110 mmHg (Approx.)
The central venous pressure is assumed to be negligible as per the given statement.
CVP = 0 mmHg
TPR = (MAP - CVP) / CO = (110 mmHg - 0 mmHg) / 5200 mL/min = 0.0211 mmHg.min.mL-1
b) Calculation of O2 content in arterial and mixed venous blood:
Arterial blood and mixed venous blood have different oxygen content due to oxygen consumption by the body cells.
Arterial blood O2 content:
O2 content = (Hb x SaO2 x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x PaO2)
Hb = 14 g/dL
SaO2 = 100%
PaO2 = 100 mmHg
O2 content = (14 g/dL x 100% x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x 100 mmHg)
O2 content = 19.14 mL O2/dL
Mixed venous blood O2 content:
O2 content = (Hb x SvO2 x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x PvO2)
Hb = 14 g/dL
SvO2 = 40%
PvO2 = 40 mmHg
O2 content = (14 g/dL x 40% x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x 40 mmHg)
O2 content = 14.25 mL O2/dL
c) Calculation of O2 consumption rate:
O2 consumption rate is the amount of oxygen consumed by the body in a minute.
O2 consumption rate = CO x (CaO2 - CvO2)
CO = 5200 mL/min
CaO2 = 19.14 mL O2/dL
CvO2 = 14.25 mL O2/dL
O2 consumption rate = 5200 mL/min x (19.14 mL O2/dL - 14.25 mL O2/dL)
O2 consumption rate = 2548 mL/min
d) Calculation of O2 content in arterial blood post-CO exposure:
When arterial blood passes through the lungs, the oxygen saturation returns to normal as carbon monoxide (CO) is removed from the hemoglobin.
O2 content = (Hb x SaO2 x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x PaO2)
Hb = 14 g/dL
SaO2 = 100%
PaO
2 = 100 mmHg
O2 content = (14 g/dL x 100% x 1.34 mL O2/g Hb) + (0.003 mL O2/dL x 100 mmHg)
O2 content = 19.14 mL O2/dL
Note: As given in the question, arterial PaO2 is not affected by CO.
e) Estimation of mixed venous blood PaO2 following CO exposure:
When the body cells do not receive enough oxygen, the saturation of mixed venous blood decreases. According to the 50% COHb curve, the mixed venous blood saturation is 30% when PaO2 is 20 mmHg.
Explanation:
Breathing pure oxygen increases the amount of oxygen in the alveoli and raises the oxygen partial pressure. The higher partial pressure of oxygen leads to increased diffusion of oxygen from the alveoli into the blood. Breathing pure oxygen for an extended period can result in lung atelectasis, which is the partial or complete collapse of one or more parts of the lungs. This occurs due to the absorption of pure oxygen by the lung tissues. The absorbed oxygen displaces the nitrogen, which is normally present in the lungs and helps keep the air sacs open. The absence of nitrogen causes the air sacs to collapse.
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QUESTIONS 8 Choose all of the following functions of the skeleton O Support
O protection O movement O electrolyte balance O blood cell reduction
O acid-base balance QUESTION 9 Choose all of the correct function of the muscular system O movement O stability O inhibits communication O controls body openings O heat production
The correct functions of the skeleton are support, protection, movement, blood cell production, electrolyte balance, and acid-base balance.
Support: The skeleton provides structural support for the body, giving it shape and rigidity. It forms the framework that supports and holds together the various tissues and organs.
Protection: The skeleton protects vital organs and tissues from injury. For example, the skull protects the brain, the ribcage protects the heart and lungs, and the vertebral column protects the spinal cord.
Movement: The skeleton, along with muscles and joints, allows for movement and locomotion. Muscles attach to bones, and when they contract, they create movement by exerting force on the skeleton.
Blood cell production: Within the bone marrow, certain bones are involved in the production of new blood cells. The bone marrow contains hematopoietic stem cells that give rise to red blood cells, white blood cells, and platelets.
Electrolyte balance: Bones act as a reservoir for minerals, particularly calcium and phosphorus. They release and store these minerals to maintain proper electrolyte balance in the body.
Acid-base balance: The skeleton helps regulate acid-base balance by acting as a buffer system. It can release or absorb minerals to help maintain the pH balance of the body fluids.
Therefore, the correct functions of the skeleton are support, protection, movement, blood cell production, electrolyte balance, and acid-base balance.
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81-90. Colette was so frightened by her ride on the new roller coaster at Great Adventures that she discovered at the end of the ride that she had wet her pants. Give the name of this condition and explain the physiology behind this embarrassing occurrence. 91-100. Give the effect of the following 2 drugs-Nicotine and Norepinephine.
The condition Colette experienced is called urinary incontinence, specifically stress urinary incontinence.
It is the involuntary leakage of urine that occurs during physical exertion, such as laughing, coughing, sneezing, or in this case, being frightened on a roller coaster.
The physiology behind stress urinary incontinence involves the weakening or dysfunction of the muscles and tissues that support the bladder and control urination. These muscles and tissues are collectively known as the pelvic floor muscles. When subjected to sudden increases in abdominal pressure, such as during intense physical activities or emotional stress, the weakened pelvic floor muscles are unable to adequately support the bladder and prevent urine leakage.
Now moving on to the effects of the two drugs:
Nicotine is a stimulant found in tobacco products. It acts on the central nervous system and peripheral organs. Nicotine stimulates the release of various neurotransmitters, including dopamine, norepinephrine, and acetylcholine. It has stimulating effects, increasing heart rate, blood pressure, and alertness. It can also act as a vasoconstrictor, narrowing blood vessels.
Norepinephrine is a neurotransmitter and hormone that plays a role in the body's stress response. It is released by sympathetic nerve fibers and acts on various organs. Norepinephrine increases heart rate, constricts blood vessels, raises blood pressure, and enhances alertness and focus as part of the body's fight-or-flight response.
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How does digitalis decrease heart rate? Explain full
process/mechanism.
Digitalis decreases heart rate through its action on the autonomic nervous system and the heart muscle cells.
Digitalis works by inhibiting the sodium-potassium ATPase pump, which leads to an increase in intracellular sodium concentration. This increase in intracellular sodium then inhibits the sodium-calcium exchanger, causing an increase in intracellular calcium concentration. The increased calcium concentration enhances the contractility of the heart muscle cells, leading to increased force of contraction. Simultaneously, digitalis also activates the vagus nerve, which releases acetylcholine, a neurotransmitter that decreases heart rate by slowing down the firing rate of the sinoatrial (SA) node, the natural pacemaker of the heart. This combined effect of increased contractility and decreased heart rate results in an overall decrease in heart rate.
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Which one of the following statements is CORRECT? Select one: a. Action potentials are variable-strength signals that are transmitted over short distances only. b. Action potentials may be transmitted in either direction along an axon, towards the axon terminals or towards the dendrites. c. Excitatory post-synaptic potentials (EPSPS) decrease in amplitude as they travel.
d. Post-synaptic potentials are all-or-none in amplitude. e. Post-synaptic potentials are always initiated at the axon Hillock.
The correct statement among the following options is Action potentials may be transmitted in either direction along an axon, towards the axon terminals or towards the dendrites.
Action potential An action potential is a spike-like occurrence in electrical potential fluctuations that passes along the membrane of a cell, such as the membrane of an axon of a neuron, muscle cell, or gland cell, among other cell types. It is characterised by a rapid rise in potential, followed by a slower fall, resulting in a short-lived increase in membrane potential that spans a few milliseconds.
AxonAn axon is a long, slender projection of a nerve cell or neuron that transmits electrical impulses away from the neuron's cell body or soma to the other neurons, muscles, and glands. The terminal arborization of the axon is referred to as the axon terminal.
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To increase air movement in breathing, patients with emphysema increase their force of
breathing by utilising accessory muscles. Explain how using accessory muscles allows for
greater air movement in and out of the lungs.
Using accessory muscles allows patients with emphysema to increase air movement in and out of the lungs by assisting in expanding the chest and increasing the force of breathing.
Patients with emphysema, a chronic lung condition characterized by the damage of air sacs in the lungs, often experience difficulty in breathing due to the loss of elasticity in their lung tissues. To compensate for this loss and increase air movement, they engage the accessory muscles involved in respiration.
Accessory muscles are secondary muscles that aid in breathing when the primary muscles, such as the diaphragm and intercostal muscles, are unable to generate enough force on their own.
In patients with emphysema, the weakened lung tissues result in reduced lung capacity and impaired air flow. By activating the accessory muscles, these patients can enhance the efficiency of their respiratory system.
The accessory muscles involved in breathing include the sternocleidomastoid, scalene, and trapezius muscles, among others. When these muscles contract, they assist in expanding the chest cavity and elevating the ribcage, allowing for a greater volume of air to be inhaled. This expansion creates a larger pressure gradient between the lungs and the external environment, facilitating increased air movement into the lungs.
During exhalation, the accessory muscles also play a role. They help to forcefully compress the chest and decrease the volume of the lungs, expelling a larger volume of air. This forceful expiration aids in removing stale air and waste gases from the lungs, promoting better gas exchange and ventilation.
In summary,The use of accessory muscles in patients with emphysema is a compensatory mechanism that helps overcome the limitations imposed by damaged lung tissues. By actively engaging these secondary muscles, individuals with emphysema can increase their force of breathing and improve air movement in and out of their lungs.
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Identify two pairs of muscles in the superior appendage that are antagonists
The two pairs of muscles in the superior appendage that are antagonists are the biceps brachii and the triceps brachii, and the flexor carpi radialis and the extensor carpi radialis.
This is the explanation regarding these two pairs of muscles:Biceps brachii and Triceps brachii musclesThe biceps brachii muscle is located in the front part of the upper arm. It is responsible for bending the elbow joint. While the triceps brachii muscle is located in the back part of the upper arm. It is responsible for extending the elbow joint. These two muscles, therefore, are considered to be antagonistic.Flexor carpi radialis and Extensor carpi radialis musclesThe flexor carpi radialis and the extensor carpi radialis muscles are also considered to be antagonistic. These two muscles are located in the forearm. The flexor carpi radialis muscle is responsible for flexing the wrist joint while the extensor carpi radialis muscle is responsible for extending the wrist joint.
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