An enzyme becomes denatured when the active site changes shape (Option A is correct).
What is the enzyme's active site?The enzyme active site refers to a molecular domain in the enzyme that binds to the substrate during a chemical reaction, which changes of tridimensional shape after the denaturation of the enzyme.
Enzyme active site is different to the binding site for cofactors, which may increase the rate of a given chemical reaction.
In conclusion, an enzyme becomes denatured when the active site changes shape (Option A is correct).
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bone-targeted delivery of tgf-beta type 1 receptor inhibitor rescues uncoupled bone remodeling in camurati-engelmann disease.
Camurati-Engelmann disease (CED) is a genetic bone-modelling disorder mainly caused by mutations in the gene that encodes transforming growth factor-β1 (TGF-β1). To achieve bone-targeted delivery of TR1I, it is designed a new drug that conjugated TR1I and bisphosphonate through a metabolically cleavable linker. It is characterized by increased bone density primarily affecting the long bones of the arms and legs and the skull.
CED is a rare bone dysplasia characterized by diffuse diaphyseal osteosclerosis. Skull base involvement in CED can result in hypopituitarism but is seldom reported. Our objective was to report a patient with acquired hypopituitarism due to CED and assess the management challenges. The thickening of these bones leads to pain, a waddling gait, muscle weakness, and extreme fatigue.
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an avid gardener in eastern north america begins to have a fever and cough. a sample from her lungs contains yeast cells and pus. she may be infected with:
Blastomyces dermatitidis.
A dimorphic fungus called Blastomyces dermatitidis produces blastomycosis, an invasive and sometimes fatal fungal illness that can occasionally affect both humans and other animals. It often lives near a body of water, such as a lake, river, or stream, in soil and damp, decomposing wood. Indoor growth can also happen, for instance, in piled-up trash in wet sheds or shacks. The fungus is endemic to certain regions of eastern North America, particularly boreal northern Ontario, southeastern Manitoba, Quebec south of the St. Lawrence River, portions of the U.S. Appalachians and interconnected eastern mountain chains, the west bank of Lake Michigan, the state of Wisconsin, and the entire Mississippi Valley, including the valleys of some major tributaries like the Ohio River.
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Ligaments are very strong but resistant to stretch. Which protein fiber probably predominates?.
Ligaments are very strong but resistant to stretch. Collagen protein fiber probably predominates.
Collagen is the main and the most abundant protein found around the skin, tissues, muscles, and bones. It is About 30 percent of the total protein in the body.
It connects different structures in the body by serving as glue. Collagen is also found in the teeth, and blood vessels. Collagen can be a rigid or tendon or can be both in the form of cartilage.
There are four types of collages. Type I gives structure to the bones skin, teeth and tendons. Type II is loosely bound fiber. Type III deals with the structure of organs, muscles, and arteries. Type IV is found in the basement membranes.
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rrna signature sequences can be used to place microorganisms in the correct domain. question 8 options: 1) true 2) false
The rRNA signature sequences can be used to place microorganisms in the correct domain is True.
rRNA- All cells require ribosomes, which are the main building block of non-coding RNA known as ribosomal ribonucleic acid (rRNA). Protein synthesis is carried out by rRNA, a ribozyme, in ribosomes.
Signature Sequence- Proteins having a certain structure or function have continuous patterns of amino acids 10–50 residues long known as signature sequences.
Microorganism- A living thing that can only be observed under a microscope. Protozoa, algae, fungus, and bacteria are all examples of microorganisms. Viruses are occasionally categorized as microbes even though they are not thought of as living things.
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Explain why heart failure often results in renal failure.
Answer:
Relatively recent research has shown that heart failure is a significant risk factor for kidney disease. When the heart is no longer pumping efficiently it becomes congested with blood, causing pressure to build up in the main vein connected to the kidneys and leading to congestion of blood in the kidneys, too.
Reference:
https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/kidney-heart-link
Which event must happen for energy to be released from ATP?
The oxygen atoms surrounding a phosphate are removed.
More oxygen atoms are added to each phosphate group.
A new phosphate group is added to the molecule.
A phosphate group is broken from the molecule
For energy to be released from ATP, a phosphate group is broken from the molecule to form ADP. Therefore option (D) is the correct answer.
What is ATP and when is energy released from it ? Adenosine triphosphate, also known as ATP ,the primary energy currency of cells.
ATP is an RNA nucleotide with a chain of three phosphates, according to its structural makeup. Adenine, a nitrogenous base, a chain of three phosphates, and ribose, a five-carbon sugar, are all joined together in the heart of the molecule.
The three phosphate groups are identified as alpha, beta, and gamma, according on how close to the ribose sugar they are. Phosphonhydride bonds, often known as "high-energy" bonds, are the bonds that connect the phosphate groups.
In hydrolysis (water-mediated breakdown) reaction, one of these bonds is broken, releasing a sizable quantity of energy.
Therefore option (D) is the best choice.
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Because bacteria frequently grow on poorly stored food, this often leads to what?
Poorly stored food usually experiences spoilage or foodborne illnesses because bacteria often thrive there.
Bacteria can grow and breed rapidly when food is not stored properly. Microorganisms called bacteria can contaminate food and create toxins, which reduce the quality and safety of food. When food loses its taste, texture, appearance, or nutritional value, it becomes unpalatable or unsafe to eat. This is called food spoilage.
Foodborne infections can occur more frequently when dangerous bacteria are present in improperly stored food. These infections can be spread by consuming contaminated food, which can cause symptoms such as nausea, vomiting, diarrhea, abdominal discomfort and, in some circumstances, more serious health problems.
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consider the following structural levels chemical, tissue organ, celluar, organimsional, systemic. whih of the following choices
The human body's life processes are preserved at a number of structurally distinct levels, including the biochemical, cell, tissues, organs, organ system, and organism levels.
The smallest unit of these special compounds, called elements, which make up all living and non-living objects is the atom. Atoms merge to create molecules. All components in the body are made up of molecules, which can be little, medium-sized, or huge.
Cells, which are composed of a wide variety of chemicals, are the building blocks of all living things. The tiniest autonomous living entity in the body are cells. The human body is made up of numerous different cell kinds, each serving a specific purpose.
A cell membrane, or thin layer, surrounds a jelly-like cell fluid containing microscopic organ-like components called organelles in every human cell. Organelles come in a variety of forms, each serving a specific purpose. Cells in the body are arranged into tissues, much like in other multicellular creatures. A tissue is made up of a collection of related cells that collaborate to carry out a certain task. In humans, there are four primary tissue types (muscular, epithelial, nervous and connective). An organ is a recognizable biological structure made up of two or more tissue types. Organs frequently serve a specific physiological purpose. An organ system is a group of organs that cooperate to carry out a particular task.
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What is lactase? Select ALL that apply
Protein
Carbohydrate
Lipid
Nucleic Acid
Enzyme
you are told to cut a dissection animal along two planes so that both kidneys are observable in each section. the two sections that can meet this requirement are the and sections.
The two sections that can meet this requirement are the transverse section and the frontal sections.
Transverse Section- A transverse section is an incision that is performed across the body of an animal, a plant, an organ, or a tissue. People most frequently refer to it as the gap between left and right. An organism's transverse section often extends between its lateral ends from left to right or the other way around.
Frontal Section- A frontal section is a slice of the body that cuts perpendicular to the median plane and divides the body into the dorsal and ventral halves.
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bones in different vertebrates are if they have the same evolutionary origin but now differ in structure and function.
Answer:
homologous structures
Explanation:
something like bat wings and human hands
they evolved from a common ancestor, but are now different and used differently
please help
identify the process shown below and explain how it works
(use the picture/file to help you with this question)
thank you
The given process is exocytosis. In exocytosis, the molecules move from the cell to outside the cell.
What is exocytosis?In process of exocytosis, the molecules move from the cell to outside the cell. This process is important for the removal of waste.
Steps of exocytosis:
Molecule-filled vesicles are moved from a cell's inside to the cell membrane.The cell membrane and the vesicle membrane are joined.The contents of the vesicle are released from the cell when the vesicle membrane and cell membrane fuse.
There are different types of exocytosis that are constitutive exocytosis, regulated exocytosis.
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choose the incorrect statement. when a small fish (e.g. a goldfish) is placed in water with a temperature gradient, it will explore the environment until its optimum temperature changes to the temperature of the water. after an ectotherm has acclimated to a lower temperature, its critical temperature is lower even though its optimal metabolic rate is the same. terrestrial ectotherms rely primarily on behavioral thermoregulation to help them achieve their optimal metabolic rates. a terrestrial ectotherm can achieve a body temperature higher than ambient air temperature using heat gain by radiation or by conduction.
When a small fish (e.g. a goldfish) is placed in water with a temperature gradient, it will explore the environment until its optimum temperature changes to the temperature of the water.
Temperature gradient- The only difference in temperature across a certain distance between two sites is referred to as a temperature gradient. Between the two places, there are variations in air pressure because of the temperature differential. As the atmosphere strives to equalize the air pressure, the air pressure difference causes winds to develop.
Optimum Temperature- The temperature at which a process, such the growth of a particular organism or the activity of an enzyme, is best carried out.
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Scientists who study
ocean temperatures
have seen
A. that the ocean is recently becoming colder
B. that the ocean is recently becoming warmer
C. that the ocean temperatures are not changing at all
Copyright ©ang International Academy of Scienes. All Rights Rerved
Answer:
scientists who study the ocean have seen b the ocean is becoming warmer
6. What does the term "directionality" refer to when discussing polynucleotides?
Answer:
Polynucleotides have two ends that are different from each other.
Explanation:
infiltrating s100a8 myeloid cells promote metastatic spread of human breast cancer and predict poor clinical outcome
The mechanisms of metastasizing breast cancer are complex. the goal was to identify tumor-induced stromal modifications that affect metastatic cell behavior, and function as better marks for therapy.
Dual-species gene expression analysis was performed to identify stromal changes in cancer-bearing tissue for three different metastatic Breast cancer xenografts. In pre-clinical models of Breast cancer, the systemic need for S100A8+ myeloid cells-including myeloid-derived suppressor cells (MDSCs)-was stimulated by tumor-derived factors.The need for S100A8+ myeloid cells was reduced by inhibition of tumor-derived factors leading to fewer metastases and fewer primary tumors. Those myeloid-derived suppressor cells possess the ability to suppress T cell accumulation upon co-culture.
The release of macrophage inhibitory factors activates the need for S100A8+ myeloid cells systemically. Inhibition of MIF leads to delays in lower metastatic burden and tumor growth. In enhancing cancer progression independent of their suppressive activity on T cells, there is the recruitment of S100A8+ myeloid cells to secondary sites in xenograft models and primary tumors of Breast cancer.
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Alkali metals have the properties of metals except they are less dense and:
More brittle
Softer
Less reactive
More valuable
Alkali metals have the properties of metals except they are less dense and softer (option B).
What are alkali metals?Alkali metals are chemical elements that belong to Group 1 of the periodic table.
With the exception of hydrogen, they (alkali metals) are characterized by being soft, have low melting point, shiny light and very reactive.
Alkali metals include the following:
lithium (Li)sodium (Na)potassium (K)rubidium (R)cesium (Cs)francium (Fr)According to this question, alkali metals have the properties of metals, however, they are less dense and softer than metals.
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If meiosis produced sperm and eggs but did not involve 2 rounds of cell division
(i.e. if it more closely resembled mitosis), the offspring of a mating event would
have
the amount of DNA as the parents.
half
equal
four times
twice
Answer:
half
I hope this helps
Explanation:
BECAUSE THE DEVISTION IS BY MEIOSIS NOT MITOSIS
A group of biology students tests the growth of bacteria under different conditions. The students apply the same amount of bacteria to identical Petri dishes enriched with nutrients, then place each plate at a different temperature. The bacteria are allowed to grow for three days, after which the number of bacterial colonies on each plate is counted. What is the dependent variable in this experiment?
A.
the time of day that the experiment is performed
B.
the temperature at which the colonies grew
C.
the nutrient type present in the Petri dishes
D.
the number of bacterial colonies after three days
Answer:
D
Explanation:
The dependent variable is dependent on the independent variable. The dependent variable is thus the result of the experiment.
A gastroenterologist is a doctor who treats problems of the esophagus, stomach, and intestines. Which organ system is cared for by this type of doctor?.
Digestive system is cared for by Gastroenterologist.
What organs are the focus of gastroenterologists?The digestive system includes the gastrointestinal tract (esophagus, stomach, small intestine, large intestine, rectum, and anus), as well as the pancreas, liver, bile ducts, and gallbladder. A gastroenterologist is a specialist with knowledge of the disorders and diseases that affect the digestive system.
Who uses the digestive system to treat illnesses?The liver, pancreas, and small intestine can all be transplanted. Numerous medical professionals can aid in the diagnosis and treatment of digestive issues. A physician specialist with further training in the diagnosis and management of digestive diseases is known as a gastroenterologist.
What are the symptoms of Gastrologist?These are the some symptoms of Gastroenterology disease:
Abdominal pain and discomfort.Bleeding in the digestive tract.Constipation and Diarrhoea.Difficulty Swallowing.Severe and persistent Heartburn/indigestion.Stomach upset, nausea, vomiting.Ulcers.Unexplained weight loss.What types of conditions do Gastroenterologists treat?It covers both common and significant diseases such hepatitis, gastroesophageal reflux disease (heartburn), peptic ulcer disease, colitis, gallbladder and biliary tract disease, nutritional issues, irritable bowel syndrome (IBS), and pancreatitis.
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For the location and time interval represented by these rock layers, when did the most drastic and sudden change in life forms occur?
A.
376 million years ago
B.
370 million years ago
C.
360 million years ago
D.
382 million years ago
Answer:
D
Explanation:
i honestly don't know but here is my answer
Answer: ITS 360!!!!!!!!
Explanation: 382 IS WRONG!!!!!!!
marleen suffered a stroke in the underside of the right temporal lobe. which brain function is likely to be affected?
The brain function that is likely to be affected is the facial recognition.
What is stroke?Stroke is defined as a medical emergency that affects the cerebrovascular system whereby a blood vessel in the brain is blocked thereby reducing the blood flow to that particular part of the brain.
The right temporal lobe of the brain is responsible for learning and memorizing non-verbal information, recognizing information, and determining facial expressions.
Therefore, a stroke that affects the right temporal lobe of the brain is likely to affect the ability of the individual to be able to facially recognise another person.
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Compare the species richness, species diversity, and species evenness in the two areas. Describe two factors you think
could account for the differences in species richness/diversity/evenness in the two areas.
!!Please answer in 2 sentences!!
Species richness and species diversity are two crucial metrics ecologists employ to define the make-up of a community.
A community's species richness is determined by how many distinct species it contains. E.g., the second community would have a substantially higher species richness than the first if we identified 30 species in one community and 300 species in another.Near the equator, where there is a high concentration of solar energy, warm temperatures, abundant rainfall, and little seasonal variation, are typically where communities with the highest species richness can be found. Near the poles, which receive less solar energy and are colder, drier, and less conducive to life, are communities with the lowest species richness.The complexity of a community is gauged by its species diversity. It depends on both the community's species richness (the number of different species present) and species evenness (the relative abundances of those species).Greater species diversity would be seen in a forest community with 20 distinct tree species than one with only 5 distinct tree species .Numerous interrelated biotic (living things) and abiotic (non-living) factors contribute to the structure of a community (living organism-related): the climate of the communitythe location of the community geographicallyThe environment's heterogeneity (patchiness)how often disturbances or disruptive incidents occurinterspecies interactions.Learn more about species diversity here:
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Lion vs elephants digestion lab I need the answer sheet.
As a result, we can observe that your query isn't full. To help you better comprehend the concept, a broad review of Medicare health plans and their eligibility is provided.
WHAT IS LION VS ELEPHANTS DIGESTION LAB ?Lions consume meat, which requires robust fluids for digestion that aids in the breakdown of food. The lion's stomach is divided into four sections: the rumen, reticulum, omasum, and abomasum. While in the elephant, the stomach mostly serves as a storage space for food and digestion occurs in the cecum, which is attached to the big intestine, these chambers have microbes that aid in the breakdown of dietary materials.
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Phytoplankton
strainer
Seaweed
Aquatic Food Web
Sea Lice
Crab
Lobster
Fish
Seagull
incidence of abnormalities of the second and third cervical vertebral junction in dogs with atlantoaxial instability: a multicenter study
There is a significantly higher incidence of anomalies affecting the C2/3 in association with AAI. In conjunction with AAI, intervertebral disc-related anomalies are the most frequent pathological finding affecting the C2/3.
What is craniocervical junction ?The craniocervical junction (CCJ) is a term used to describe the interface between the skull and cervical spine, and more specifically it includes the occipital bone surrounding the foramen magnum and the first and second vertebrae.
Conservative treatment of craniocervical instability includes physical therapy and the use of a cervical collar to keep the neck stable. Patients with more severe symptoms often undergo cervical spinal fusion.Learn more about Craniocervical junction here:
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The primary function of light absorption by photosystems i and ii is to produce __________.
The primary function of light absorption by photosystems I and ii is to produce a free electron, full of energy.
Photosynthesis is the process by which plants or algae produce oxygen and energy using Sunlight, carbon dioxide, and water.
Photosystem I and photosystem II help plants to absorb light and radiation. The absorption of light in Photosystem II and then in I excites a free electron which is then passed by an electron transport chain.
This electron transport chain uses the energy of electrons to form a protein gradient that can be used as an energy source.
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amino acids are those amino acids that do not need to be obtained from the diet because the body is capable of synthesizing (producing) them.
Nonessential amino acids are those amino acids that do not need to be obtained from the diet because the body is capable of synthesizing (producing) them.
Nonessential implies that our bodies can make the amino acid even if we don't get it from food. Alanine, aspartic acid, arginine, serine, asparagine, cysteine, glycine, glutamine, glutamic acid, proline, and tyrosine are examples of nonessential amino acids.
Nonessential amino acids help with tissue development and repair, immunity, the formation of red blood cells, and hormone synthesis. However, unlike essential amino acids, a healthy body can produce these proteins if provided with good protein sources containing essential amino acids.
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1. the nuclear dna content of a single sperm cell in the beach mouse (peromyscus polionotus) is 3.57 picogram (pg). what would be the expected nuclear dna content of a(n)
Answer:
The primary spermatocyte of prophase 1 contain double amount of DNA (3.57×2= 7.14pg) as it is diploid in nature.
Explanation:
Most DNA in mature human sperm is bound to protamine, as somatic histones are replaced during spermiogenesis. However, biochemical analyses of human sperm proteins indicate retention of some histones resulting in a nuclear protein composition that is about 90% protamine and 10% histone.
Primary spermatocyte produces four spermatids. During spermatogenesis there are two cellular divisions, but only one replication of DNA so that each spermatid has 23 chromosomes (haploid), one from each pair in the original primary spermatocyte. It begins with a diploid spermatogonium in the seminiferous tubules, which divides mitotically to produce two diploid primary spermatocytes.
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suppose you discover a cell that is 200 micrometers in diameter. upon closer examination, you find that the dna is not housed within a nucleus and you find no other membrane-bound organelles. this organism is most properly categorized as:
If a cell is found to have no nucleus and no membrane bound organelles on observation then it is categorized as a prokaryotic cell.
Prokaryotic cell: Any cell that does not have a delineated nucleus or membrane-bound organelles. All other forms of life are eukaryotic, whereas organisms in the domains Bacteria and Archaea are based on the prokaryotic cell. Prokaryotic species, on the other hand, are exceedingly prevalent and account for a large portion of the biomass on Earth.The tiniest eukaryotic cells are substantially larger than prokaryotic cells. Prokaryotic cells are often smaller because they lack enough DNA to produce the proteins required to form an ultra-efficient membrane.The nucleoid region, which is an atypically shaped area that houses the cell's DNA and is not encased in a nuclear envelope, is present in prokaryotic cells.A prokaryote's cytosol is where all of the organism's responses take place.Hence, the correct answer is prokaryotic cell.
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